CTFA Annual Report 2022

The aim was to provide the CTPA and their member companies with a better understanding of the regulatory landscape in South Africa as well as the interaction of the CTFA with various national, international and continental stakeholders. It was also aimed at providing a better understanding of the Foodstuff, Cosmetics and Disinfectant Act, (Act 54 of 1972) as well as the importance of the Draft Regulations Relating to Labelling, Advertising and Composition of Cosmetics, R.1469, 22 December 2017. CTFA - German Cosmetic, Toiletry, Perfumery and Detergent Association (IKW), July 2022: CTFA hosted a webinar with IKW regarding Safety Assessor training with renowned international presenters that included, Dr Elisabeth Gerber – a Senior Assessor/Eurotox Registered Toxicologist, Dr Nicole Braun from the Institute for Experimental Dermatology at the Witten/Herdecke University and Mr W. Steiling. Dr Gerber presented on the principles in Safety Assessment of finished cosmetic products. In various cosmetic regulations worldwide, a cosmetic safety assessment for human health has to be completed for every cosmetic product. In addition, cosmetic products should be correctly labelled and packaged with appropriate INCI (International Nomenclature for Cosmetic Ingredients) listing and warnings. Dr Gerber also gave an overview of the parameters which must be considered during the safety assessment of cosmetics, starting with the toxicological evaluation of the ingredients, followed by skin compatibility assessment of the cosmetic formula and other legally required considerations. Dr Braun gave an overview of dermatological compatibility tests; there are numerous tests available to determine the compatibility of cosmetics on human skin. In addition to standard tests, there are other tests such as, the one-time closed photopatch test to exclude suspected phototoxic reactions or a special light tolerance photo test to exclude Mallorca acne, preferably used for sunscreens. Mr W Steiling presented on Dermal Absorption or Percutaneous Penetration of Ingredients. For the safety evaluation of cosmetic ingredients, their dermal bio-availability is an important factor. Cosmetic ingredients’ bio-availability is conservatively defined as the amount found in the living epidermis and/or dermis as well as in the circulatory system when topically exposed under intended use conditions. Following this definition, amounts bound to the horny layer (stratum corneum) as the outer skin barrier, must be separated as non-bioavailable. Three terms have been defined to make substance localisation during the process of penetration specific and clear: “dermal adsorption” (on or within the stratum corneum), “dermal COSMETIC TOILETRY AND FRAGRANCE ASSOCIATION OF SOUTH AFRICA 13